With work by Uruguayan artists covering most of the interiors (literally), the Estancia Vik ranch, which sits on 4,000 sprawling acres, is the ultimate art hotel. The graffiti murals, oil paintings, friezes, sculptures and mixed-media installations are by the country’s biggest art stars. Its new, more modernist sister property Playa Vik, by Montevideo-born architect Carlos Ott (nearby, on a beach), follows the same design approach (this time bringing in some international talent): give artists free reign, so every square inch reads like an art installation you can sleep in.